Mission statement:

Architecture of the mind

Our mission is to understand how networks of neurons enable the cognitive functions of the brain, including consciousness, perception, movement, learning and social interaction, in health and disease.

The research program integrates three levels of biological complexity:
  • genetic and molecular approaches
  • cellular approaches and network function
  • system and behavioral approaches

The research program is carried out in 19 research groups. In addition, the NIN includes the Netherlands Brain Bank and participates in the Spinoza Centre for Neuroimaging

Scientific Director Pieter R. Roelfsema, PhD
Vice Director Chris I. de Zeeuw, PhD
Managing Director Ronald van der Neut, PhD




Recent Publications

Hamada, M., and Kole, M.H. Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability. Journal of Neuroscience, in press.


Ahmadlou, M., and Heimel, J.A. Preference for concentric orientations in the mouse superior colliculus. Nature Communications 6 (2015) 6773. [pdf]


Hoogland, T.M., De Gruijl, J.R., Witter, L., Canto, C.B., and De Zeeuw, C.I. Role of synchronous activation of cerebellar Purkinje cell ensembles in multi-joint movement control. Current Biology, in press. [abstract]


Kros, L., Eelkman Rooda, O.H., Spanke, J.K., Alva, P., Van Dongen, M.N., Karapatis, A., Tolner, E.A., Strydis, C., Davey, N., Winkelman, B.H., Negrello, M., Steuber, V., Van den Maagedenberg, A.M., De Zeeuw, C.I., and Hoebeek, F.E. Cerebellar output controls generalized spike-and-wave discharge occurence. Annals of Neurology, in press.


Saiepour, H.D., Rajendran, R., Omrani, A., Ma, W.P., Tao, H.W., Heimel, J.A., and Levelt, C.N. Ocular dominance plasticity disrupts binocular inhibition-excitation matching in visual cortex. Current Biology, in press.


Kamermans, M. Change the neural code, change the message. Nature Neuroscience, in press. [abstract]


Shan, L., Bao, A.M., and Swaab, D.F. The human histaminergic system in neuropsychiatric disorders. Trends in Neurosciences, in press.


Testa-Silva, G., Verhoog, M.B., Linaro, D., De Kock, C.P., Baayen, J.C., Meredith, R.M., De Zeeuw, C.I., Giugliano, M., and Mansvelder, H.D. High bandwidth synaptic communication and frequency tracking in human neocortex. PLoS Biology 12 (2014) e1002007. [abstract]


Pooresmaeili, A., and Roelfsema, P.R. A growth-cone model for the spread of object-based attention during contour grouping. Current Biology, in press.


Van Hemmen, J., Veltman, D.J., Hoekzema, E., Cohen-Kettenis, P.T., Dessens, A.B., and Bakker, J. Neural activation during mental rotation in complete androgen insensitivity syndrome: the influence of sex hormones and sex chromosomes. Cerebral Cortex, in press.


Stargardt, A., Swaab, D.F., and Bossers, K. The storm before the quiet: neuronal hyperactivity and Aβ in the presymptomatic stages of Alzheimer's disease. Neurobiology of Aging, in press.


Kranz, G., Hahn, A., Kaufman, U., Kublbock, M., Hummer, A., Ganger, S., Seiger, R., Winkler, D., Swaab, D.F., Windischberger, C., Kasper, S., and Lanzenberger, R. White matter microstructure in transsexuals and controls investigated by diffusion tensor imaging. Journal of Neuroscience 34 (2014) 15466-15475.


Saiepour, M.H., Chakravarthy, S., Min, R., and Levelt, C.N. Competition and homeostasis of excitatory and inhibitory connectivity in the adult mouse visual cortex. Cerebral Cortex, in press.


Wang, F., Kessels, H.W., and Hu, H. The mouse that roared: neural mechanisms of social hierarchy. Trends in Neurosciences 37 (2014) 674-682. [abstract]


Van Kerkoerle, T., Self, M.W., Dagnino, B., Gariel-Mathis, M.A., Poort, J., Van der Togt, C., and Roelfsema, P.R. Alpha and gamma oscillations characterize feedback and feedforward processing in monkey visual cortex. PNAS 111 (2014) 14332-14341.


Springelkamp, H., Hohn, R., Mishra, A.,.....De Jong, P.T.V.M., ...Bergen, A.A.B., ....Van Duijn, C.M., and Hammond, C.J. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nature Communications, in press.


Piantoni, G., Van der Werf, Y.D., Jensen, O., and Van Someren, E.J.W. Memory traces of long-range coordinated oscillations in the sleeping human brain. Human Brain Mapping, in press. [abstract]


Van den Heuvel, J.K., Furman, K., Gumbs, M.C., Eggels, L., Opland, D.M., Land, B.B., Kolk, S.M., Narayanan, N., Fliers, E., Kalsbeek, A., DiLeone, R.J., and La Fleur, S.E. Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. Biological Psychiatry, in press. [abstract]


More publications




27 March 2015

HRH King Willem-Alexander paid a working visit to the Netherlands Institute for Neuroscience [news]

1 March 2015

Dries Kalsbeek and Tom van der Poll (AMC) received a TOP-grant from ZonMw of 675,000 euro.

1 January 2015

Christian Keysers has been appointed professor of Social Neuroscience at the Faculty of Social and Behavioral Sciences of the University of Amsterdam.

22 December 2014
the 5th international Art of Neuroscience competition is open: Submit your image, or movie before February 25th 2015.

see website: aon.nin.knaw

3 November 2014, Blue House, Seoul.

Inge Huitinga will sign a Memorandum of Understanding between the Netherlands Institute for Neuroscience and the Korean Brain Research Institute.

The ceremony will take place in the presence of King Willem-Alexander and Queen Maxima and President Park of South-Korea.
[photo] [photo2]

29 October 2014

The Academy of the Arts from the KNAW awarded a grant of 30,000 euro to Ysbrand van der Werf and Arnon Grunberg for a project on reading and brain activity

26 October 2014

The Russian Academy of Science awarded the Ott's medal to Dick Swaab as an outstanding scientist, who contributed greatly to the development of molecular microscopy and effective application of this method for study of human neuroendocrine pathology.


NINnews December 2013

NINnews June 2013

NINnews May 2012

NINnews October 2011

NINnews April 2011

NINnews November 2010

NINnews June 2010




17 April 2015, 16:00 h, colloquium room NIN 


Brain award lectures and ceremony


Awards for Leonardo Cerliani (scientific excellence) and
Matthew Self (best collaborative paper)

21 April 2015, 15:30 h, Erasmus University Rotterdam


Beerend Winkelman will defend his thesis entitled:


Cause and consequence of Purkinje cell signals in the cerebellar flocculus.

22 April 2015, 11:45 h, VU Amsterdam


Rebecca Astill will defend her thesis entitled:


Don't let the bedbugs bite. Sleep's beneficial effects on childhood cognitive development.